Defense Molecules

Defense Molecules

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Defense Molecules is a broad-ranging examination of defense mechanisms that have evolved in plants, invertebrates, and vertebrates. An international group of investigators consider various universal biological approaches to host protection--from cellular recognition phenomena to detailed molecular analysis of receptor, effector, and regulatory molecules. Contributions focus on basic defense mechanisms, irrespective of the organism under consideration. Some of the specific topics covered include: the role of phagocytes/macrophages in defense, non-immunoglobulin defense mechanisms, alloreactivity, T-Lymphocytes, the evolution of antibodies and major histocompatibility complex, as well as the evolution of cytokines in disease and immunosuppression.Sequence comparisons among Ig light chains and sharks and higher vertebrates E┬ŁEm are focusing our studies upon two types of primitive vertebrates, carcharine sharks (galapagos shark, Carcharinus galapagenesis; tiger shark, Galecerdo curvieri; sandbar shark, Carcharhinus ... Figure 1 is a schematic diagram illustrating the regions of a light chain and our approach to characterizing the light chains ofanbsp;...

Title:Defense Molecules
Author: John J. Marchalonis, Carol L. Reinisch
Publisher:Wiley - 1990-02-20

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